Africa: Disadvantage of late treatment start may persist for years

Starting antiretroviral therapy earlier, before the development of symptoms, is the most likely way to reduce the high death rates after treatment initiation seen in people with HIV in resource-limited settings, two large cohort analyses show. The studies also show that the major disadvantage of starting treatment late - an increased risk of death - may persist for some years, burdening already overstretched health systems with illness that could be avoided by earlier treatment.